Irritable Bowel Syndrome with Diarrhea

IBS-D is a condition that causes abdominal pain and diarrhea. Management of IBS-D can be complex and the best treatment depends on many factors. People with IBS-D should have an informed discussion with their doctor to develop an effective treatment plan.

Learn more about IBS-D symptoms

  • FDA-Approved IBS-D Therapies

    • Lotronex®

      alosetron

      Lotronex can help reduce diarrhea symptoms and abdominal pain in people with IBS-D. It works by slowing the movement of stool through the intestines. Currently, Lotronex is only FDA-approved for use in women with severe IBS-D.

      https://www.lotronex.com

    • Viberzi®

      eluxadoline

      Viberzi can help reduce diarrhea symptoms in people with IBS-D. It works by slowing the movement of stool through the intestines.

      http://www.viberzi.com

    • Xifaxan®

      rifaximin

      Xifaxin is an antibiotic that can help reduce diarrhea symptoms, abdominal pain, and bloating in people with IBS-D.

      https://www.xifaxan.com

  • Other IBS-D Therapies

    • Antidepressants

      Although antidepressants were originally developed to treat mood conditions, doctors discovered that these medicines can also treat IBS symptoms.

    • Peppermint oil

      Peppermint oil can help with some IBS symptoms. It causes the intestines to relax so they are less likely to spasm and cramp.

    • Probiotics

      Probiotics, or "good bacteria", can sometimes help with IBS symptoms. Not all probiotics are the same, so speak with your doctor to determine if any are right for you.

    • Psychological interventions

      There is some evidence that psychological therapies, like cognitive behavioral therapy, hypnotherapy, relaxation breathing, and mindful meditation, can help with IBS symptoms.